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  发表文章 （#：共同第一；*：共同通讯）

1.Yuxian Xiong^#, Bin Huang^#, Ying Yang, Xinming Fu, Ziyang Fu, Huidong Xu, Ming Liu, Dan Cao, Manman Zhang, Haibin Yang, Xiaogang Niu, Cong Yu, Hao Huang*, Contrast Between Papain-like Proteases from Mild to Severe Disease-causing Human Coronaviruses Reveals Differential Viral Innate Immune Evasion. Sci. Signal., 2023, in press

2.Dan Cao^#, Lian Duan^#, Bin Huang^#, Yuxian Xiong, Guoliang Zhang^*, Hao Huang^*, SARS-CoV-2 Papain-Like Protease Suppresses Type I Interferon Responses by Deubiquitinating STING. Sci. Signal., 2023, in press

3.Ziyang Fu^#, Bin Huang^#, Jinle Tang^#, Shuyan Liu^#, Ming Liu, Yuxin Ye , Zhihong Liu, Yuxian Xiong, Wenning Zhu, Dan Cao, Jihui Li, Xiaogang Niu, Huan Zhou, Yong Juan Zhao , Guoliang Zhang*,Hao Huang*,The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery.Nat Commun.2021,12(1),488-500

4.Yuxin Ye*, Yuxian Xiong, Hao Huang*, Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8,Commun Biol.    2020,3(1),752-766.

5.Jinle Tang^#, Yingjie Wang^#, Huan Zhou^#, Yuxin Ye, Manisha Talukdar, Ziyang Fu, Zhihong Liu, Jihui Li, Dante Neculai, Jiali Gao,Hao Huang* Sunitinib inhibits RNase L by destabilizing its active dimer conformation , Biochem J.2020,477(17),3387-3399.

6.Jinle Tang^#, Beihua Dong^#, Ming Liu, Shuyan Liu, Xiaogang Niu, Christina Gaughan, Abhishek Asthana, Huan Zhou, Zhengshuang Xu, Guoliang Zhang, Robert H. Silverman*, Hao Huang*, Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery. J. Med. Chem.2022,65,(2), 1445–1457