题目:Reversible Chemical Modifications on DNA, RNA, and Proteins that Impact
Biological Regulations
时间:10:00-11:30
地点:E-104
Born Guizhou, P. R. China, 1972.
University of Science and Technology of China (USTC), B.S., 1994.
Massachusetts Institute of Technology, Ph.D., 2000.
Harvard University, Postdoctoral Fellow, 2000-2002.
University of Chicago,
Assistant Professor 2002-2008.
Associate Professor 2008-2010.
Professor 2010-
OFFICE: GCIS 319B, 929 East 57th Street, Chicago, IL 60637
PHONE: (773)702-5061
FAX: (773)702-0805
E-MAIL:chuanhe@uchicago.edu
WEB:http://he-group.uchicago.edu
RESEARCH INTERESTS:
Our research program spans a broad range of chemical biology, nucleic acid chemistry and biology,
epigenetics, cell biology, bioinorganic chemistry, structural biology, microbiology, and genomics. We
probe the pathways and mechanisms of nucleic acids modification and demodification. We study virulence
and antibiotic resistance regulation in human pathogens. We also study selective metal ion recognition and
sensing by naturally occurring and engineered proteins, and live-cell imaging of metal ions and other small
molecules such as H2S, heme, and CO.